With the occurrence of different crises and disasters across the globe, response preparedness has become a growing issue of concern in different organizations and institutions. Hence, this study is designed to determine the Criminology students’ crisis and disaster response preparedness which could form basis for designing a college crisis response program. This descriptive study with 160 Criminology student-respondents utilized an adapted questionnaire. Through t-test and analysis of variance, results showed that Criminology students are prepared to respond to crisis as indicated by contingency planning, capacity and capability, and information management and communication. Preparedness of the Criminology students varies significantly when they are grouped according to sex. Male students are more prepared to respond to crisis and disaster particularly in terms of capacity and capability. Results imply that the Holy Cross of Davao College administration has satisfactory contingency plans, has developed sufficient capacity and capability among its community members, and has put in place information and management communication systems in response to crisis and disaster. Class continuity during crisis and disaster, securing entry into the school premises and providing immediate information to stakeholders in times of crisis and disaster remain to be challenges to the school’s crisis and disaster preparedness.