Philippine E-Journals

Hypolipidemic Activity of Ethanolic Extract of Philippine Mahogany Seed (Swietenia macrophylla)

Augustina Aira B Entredicho | Gia Victoria D Harina | Edelyn E Quimio | Paula Joy R Sanchez | Leah F Quinto

 

Abstract:

Hyperlipidemia is one of the most leading metabolic disorders that is vastly seen in this era of modernization and fast life. It can be acquired through having high calories intake, causing a deranged digestion and metabolism in our body that may be associated with a cluster of metabolic diseases (Kaimal, 2010). This metabolic condition is characterized by alterations occurring in serum lipid and lipoprotein profile due to elevated concentration of total cholesterol, low density lipoprotein, very low-density lipoprotein and triglycerides along with decrease in high density lipoprotein in the blood circulation (Thanga et al., 2013). At this time, the primary treatment for prevention of hyperlipidemia is dietary and improving lifestyles, followed by drug therapy if necessary. Many natural materials from plants have been used as an anti-hyperlipidemic drug. Furthermore, medicinal plants and their derivatives are promisingly gaining wide usage worldwide as they are a potential source of bioactive agents for medication.