HomeThe PCMC Journalvol. 14 no. 1 (2018)

Dengue Vaccine Acceptance and Associated Factors among Parents and Caregivers at the Philippine Children’s Medical Center Outpatient Department: A Hospital-Based Cross-Sectional Survey

Carla Mia A. Carandang | Michael M. Resurreccion

Discipline: medicine by specialism

 

Abstract:

BACKGROUND: The DOH has recently launched the first ever dengue vaccine that has successfully completed phase III clinical trials but an assessment of the general acceptance of the vaccine is widely lacking. OBJECTIVES: This study determined the dengue vaccine acceptance and the factors associated with acceptance as well as the knowledge, attitudes and practices on dengue fever among parents and caregivers at the PCMC-OPD. METHODS: A hospital-based cross-sectional survey was done at the PCMC-OPD using self-administered questionnaires regarding the KAP on dengue fever and vaccine acceptance. Multivariate analysis and Spearman’s rank correlation were used to determine predictors of DV acceptance. RESULTS: We found that DV acceptance among the participants was 81.3% (113 out of 139). Educational attainment, employment status, and monthly income are significantly associated with acceptance of dengue vaccine, and being female contributed to high acceptance. DV acceptance was strongly correlated with a lower income class. Educational attainment and employment status seem to affect DV acceptance but are not strong predictors. CONCLUSIONS: The DV acceptance rate of the parents and caregivers of patients consulting at PCMC-OPD was high. The most important factors associated with acceptance are educational attainment, employment status and income class. RECOMMENDATIONS: A similar study may be conducted with a larger population to study target populations in the Philippines. This kind of study can be utilized to formulate new strategies addressing the awareness and acceptance of the community for the new dengue vaccine.



References:

  1. World Health Organization. Global strategy for dengue prevention and control 2012–2020. Geneva: WHO; 2012.
  2. Edillo FE, Halasa YA, Largo FM, Erasmo JN, Amoin NB, Alera MT, et al. Economic cost and burden of dengue in the Philippines. Am J Trop Med Hyg. 2015;92(2):360-6.
  3. World Health Organization, Western Pacific Region. Emerging disease surveillance and response: dengue situation updates. Manila: WHO WPRO; 2014 [cited 2016 Feb 8]. Available from: http://www.wpro.who.int/emerging_diseases/DengueSituationUpdates/en/
  4. Edillo FE, Madarieta SK. Trends of dengue infections (1997–2008) in Cebu Province, Philippines. Dengue Bull. 2012;36:37-49.
  5. National Epidemiology Center, Department of Health. Manual of procedures for the Philippine Integrated Disease Surveillance and Response. Manila: DOH; 2008.
  6. Amarasinghe A, Wichmann O, Margolis HS, Mahoney RT. Forecasting dengue vaccine demand in disease-endemic and non-endemic countries. Hum Vaccin. 2010;6:745-53.
  7. Borja M. Final report of burden of dengue in the Philippines. Manila: Department of Health; 2007.
  8. Kwon DH, Crizaldo RL. A knowledge, attitudes and practices (KAP) study on dengue fever among the Rowenas community in the Philippines. Mediator. 2014;10(1):1-21.
  9. Department of Health. Dengue trends in the Philippines. Manila: DOH; 2015.
  10. Halstead SB, Heinz FX. Dengue virus: molecular basis of cell entry and pathogenesis, 25–27 June 2003, Vienna, Austria. Vaccine. 2005;23(7):849-56.
  11. Huang TS, Huang MC, Wang SM, et al. Knowledge, attitude, and practice of dengue disease among healthcare professionals in southern Taiwan. J Formos Med Assoc. 2013;112:18-23.
  12. Harapan H, Anwar S, Setiawan AM, et al. Dengue vaccine acceptance and associated factors in Indonesia: a community-based cross-sectional survey in Aceh. Vaccine. 2016;34:3670-5.
  13. Hadisoemarto PF, Castro MC. Public acceptance and willingness-to-pay for a future dengue vaccine: a community-based survey in Bandung, Indonesia. PLoS Negl Trop Dis. 2013;7(9):e2427.
  14. Harapan H, Anwar S, Setiawan AM, et al. Modifiable determinants of attitude towards dengue vaccination among healthy inhabitants of Aceh, Indonesia: findings from a community-based survey. Asian Pac J Trop Med. 2016;9(10):940-6.
  15. Dhimal M, Aryal KK, Dhimal ML, Gautam I, et al. Knowledge, attitude and practice regarding dengue fever among the healthy population of highland and lowland communities in central Nepal. PLoS One. 2014;9(7):e102028.
  16. Larson HJ, Jarrett C, Eckersberger E, Smith DM, Paterson P. Understanding vaccine hesitancy around vaccines and vaccination from a global perspective: a systematic review of published literature, 2007–2012. Vaccine. 2014;32(19):2150-9.
  17. Khan AA, Varan AK, Esteves-Jaramillo A, Siddiqui M, Sultana S, Ali AS, et al. Influenza vaccine acceptance among pregnant women in urban slum areas, Karachi, Pakistan. Vaccine. 2015;33(38):5103-9.