Philippine E-Journals

Reference Values for Nerve Conduction Studies in Healthy Newborns, Infants and Children in Philippine Children’s Medical Center

Mishelle Imperial | Lucy Kathrina Banta- Banzali | Rosalia Teleg

Discipline: medicine by specialism

 

Abstract:

BACKGROUND: Nerve conduction studies play a diagnostic role in the clinical evaluation of neuromuscular disorders in children. Reference ranges define the expected parameter values in diseasefree children. OBJECTIVES: To propose reference values for sensory and motor nerve conduction and late responses in upper and lower limb peripheral nerves in Filipino children 5 years and below. METHODS: Sensory nerve conduction studies on median, ulnar, radial, superficial peroneal, and sural nerves and motor nerve conduction and late response studies on median, ulnar, peroneal and posterior tibial nerves were done using standardized techniques among 100 healthy Filipino children. RESULTS: Subjects were stratified according to age groups. Reference values for the following parameters: (1) sensory conduction velocity and amplitude; (2) motor conduction velocity, amplitude and latency at distal sites; (3) F-wave latency; and (4) H-reflex latency were summarized. These were expressed as mean ± standard deviation or median (range) for values that follow Gaussian and non- Gaussian distributions. The 5th and 95th percentile values were likewise reported. Age had direct correlation with various nerve conduction parameters. Height was directly correlated with F-wave parameters of median, ulnar and peroneal nerves but not posterior tibial nerve. CONCLUSIONS: Reference standards for nerve conduction studies of commonly tested nerves of Filipino children are presented. Values are comparable to reference ranges elsewhere except for the Hreflex latency which is higher in this study.