HomeSALETTINIAN OPEN ACADEMIC REVIEWvol. 8 no. 1 (2026)

Prevalence Of Dengue Fever Among The Private Hospitals In Santiago City Towards Enhancing Healthcare Response To Dengue Cases

Marian Joyce Picio

Discipline: health studies

 

Abstract:

Dengue is a rapidly emerging vector-borne disease endemic in approximately 100 countries worldwide, including the Philippines. This study aimed to determine the prevalence of dengue fever in selected private hospitals in Santiago City and to describe the demographic characteristics of patients who tested positive for dengue by serologic testing. The study was conducted in three private hospitals: Callang General Hospital and Medical Center, Inc. (CGHMCI), Flores Memorial Medical Center (FMMC), and De Vera Medical Center, Inc. (DVMCI). A descriptive, retrospective research design was utilized, including all patients who tested positive for dengue fever using NS1 antigen and IgM antibody tests from January 2024 to June 2025. Data were obtained through documentary analysis of laboratory records, which provided information on patient age, sex, and test results. Descriptive statistics, such as frequency counts and prevalence rates per 10,000 population, were used to present the distribution of dengue cases by age group and sex. The Chi-square test for independence was used to determine significant differences in dengue prevalence across hospitals. The results showed 247 confirmed dengue cases, yielding a prevalence rate of 16 per 10,000 population. The highest incidence was observed among individuals below 15 years of age. Dengue occurrence was comparable between sexes, with 226 cases among males and 215 among females, each with a prevalence rate of 14 per 10,000. A statistically significant difference in dengue prevalence was noted across the three hospitals. The study concludes that dengue fever predominantly affects younger individuals in Santiago City, with males and females equally susceptible. The findings highlight the need for data-driven dengue prevention in Santiago City, prioritizing pediatric-focused education and risk assessment given higher cases among children under 15. Strengthening private hospital participation in surveillance and sentinel reporting can improve early outbreak detection, targeted vector control, community engagement, and collaboration efforts.



References:

  1. Alvarez, S., Beltrán, E. O. & Castellanos, J. E. (2023). Improving dengue diagnosis and case confirmation in children by combining rapid diagnostic tests,             clinical, and laboratory variables. Frontiers in Tropical Diseases, 4,             1118774. doi: 10.3389/fitd.2023.1118774
  2. Arce, N., Boonak, K., Bernasor, L. T., Salas, C. J., Putri, A., Aung, P. L., Imad, H. A., Chierakul,
  3. W., Luvira, V., Phonrat, B., Phumratanaprapin, W., &           Charunwatthana, P. (2024). Clinical and Epidemiological Characteristics of        Chikungunya and Dengue Infections in Provincial Hospitals of Davao de Oro, Philippines. https://doi.org/10.21203/rs.3.rs-4904666/v1
  4. Babaliche, P., & Doshi, D. (2015). Catching Dengue Early: Clinical Features and Laboratory Markers of Dengue Virus Infection. Journal of Association of Physicians of India, 63(5), 38–41. 
  5. Babu, D. V., Srinivas, P., Madhuri, M., & Melissa, Y. S. (2023). A hospital-based             study to investigate the clinical and haematological characteristics of patients with dengue fever. International Journal of Mosquito Research.
  6. Berba, R. P., Santos, J. A. P., Flores, K. M. G., dela Tonga, A., Galarion, M. J., Carascal, M. B., ... & MGonzales, M. L. (2021). Clinical Validation Of Biotek-            M™ Dengue Aqua Kit in the Diagnosis of Dengue Infections in the             Philippines. Southeast Asian Journal of Tropical Medicine and Public             Health, 52(1), 30-47
  7. Biggs, J. R., Sy, A. K., Ashall, J., Santoso, M. S., Brady, O. J., Reyes, M. A. J., Quinones, M. A., Jones-Warner, W., Tandoc, A., Sucaldito, N. L., Mai, H. K.,             Lien, L. T., Thai, H. D., Nguyen, H. A., Anh, D. D., Iwasaki, C., Kitamura, N.,       Van Loock, M., Herrera-Taracena, G., … Hibberd, M. L. (2022). Combining      rapid diagnostic tests to estimate primary and post-primary dengue immune          status at the point of care. PLOS Neglected Tropical Diseases, 16(5), e0010365. https://doi.org/10.1371/journal.pntd.0010365
  8. Capeding, M. R., L’Azou, M., Manalaysay, M., Vince-Woo, C. R., Rivera, R. G., Sy, A. K., Mercado, E. S., Inobaya, M. T., & Tayag, E. G. (2015). Laboratory-            confirmed Dengue in Children in Three Regional Hospitals in the Philippines      in 2009-2010. Pediatric Infectious Disease Journal, 34(11), 1145–1151. https://doi.org/10.1097/INF.0000000000000810
  9. Chakravarti, A., Kumar, A., & Malik, S. (2011). Detection of dengue infection by combining the use of an NS1 antigen based assay with antibody detection. Southeast Asian Journal of Tropical Medicine and Public Health, 42(2),     297–302. https://pubmed.ncbi.nlm.nih.gov/21710849/
  10. Chong ZL, Sekaran SD, Soe HJ, Peramalah D, Rampal S, Ng CW. (2020) Diagnostic accuracy and utility of three dengue diagnostic tests for the             diagnosis of acute dengue infection in Malaysia. BMC Infect Dis.doi:             10.1186/s12879-020-4911-5. PMID: 32164538; PMCID: PMC7069157.
  11. Creswell, J. W., & Creswell, J. D. (2018). Research Design: Qualitative,             Quantitative, and Mixed Methods Approaches (5th ed.).
  12. Gandhi, P. R., Taral, P., Patel, K., Rathod, S., & Rathwa, B. (2022). Dengue Fever: Clinical, Laboratory Profile and Outcome in Pediatric Patient. International Journal of Medical Science And Diagnosis Research, 6(1). https://doi.org/10.32553/ijmsdr.v6i1.892
  13. Islam, M. T., Sultana, S., Khaled, S., Hasan, Md. N., Masum, A. A., & Khan, M. H. (2022). Clinical and Laboratory Profile of Dengue Cases in a Tertiary Care Hospital of Bangladesh: An Archival Research. Tạp Chí Y Tế Công Cộng, 8.https://doi.org/10.53522/ytcc.vol8.03
  14. Juliansen, A., Meliani, F., Budiputri, C. L., Muljono, M. P., Heriyanto, R. S., Chandra, S., & Octavius, G. S. (2022). Clinical characteristics and laboratory parameters in differentiating pediatric Dengue fever and Dengue    hemorrhagic fever.
  15. Kamath, N., Mahyavanshi, D., Vohra, M., & Das, V. K. (2024). Clinical and laboratory profiles of dengue fever subtypes in a tertiary care hospital in    India: A retrospective study. Indian Journal of Microbiology Research, 11(3),       198–205.
  16. Kausar, S.T., Sudha Vani, T. M., & Kumari, P. R. (2024). A study of diagnostic applicability of NS1 and IgM ELISA in dengue fever in a tertiary care             hospital, Visakhapatnam. International Journal of Current Pharmaceutical           Research, 100–103. https://doi.org/10.22159/ijcpr.2024v16i5.5086
  17. Khadka RB, Neupane B, Chaudhary GP, et al. (2023) Dengue: Rapid Diagnostic Testing in a Tertiary Care Setting in Butwal, Nepal. J Pure             ApplMicrobiol.;17(1):380-384. doi: 10.22207/JPAM.17.1.28
  18. Kumar, K. S., Sirisha, Y., Reddy, B. M., & Nukala, P. K. (2022). Detailing dengue            - a study of clinical and laboratory profile of dengue patients in a tertiary             care centre.     International Journal of Advanced Research, 10(02), 983–987. https://doi.org/10.21474/ijar01/14303
  19. Narne, K. G., Koduri, A., Murali, R., & Kumar S, M. (2024). Clinical and laboratory profiles of dengue fever: Prognostic markers and implications for             management in tertiary care.  
  20. International Journal of Mosquito Research, 11(4), 10–15.  https://doi.org/10.22271/23487941.2024.v11.i4a.781
  21. Ndiaye, O., Woolston, K., Gaye, A., Loucoubar, C., Cocozza, M., Fall, C., Dia, F., Adams, E. R., Samb, M., Camara, D., Sadio, B. D., Diagne, C. T.,             Weidmann, M., Faye, O., Fitchett, J. R. A., Sall, A. A., & Diagne, C. T. (2023).            Laboratory evaluation and field testing of dengue NS1 and IGM/IGG rapid            diagnostic tests in an epidemic context in Senegal. Viruses, 15(4),904. https://doi.org/10.3390/v15040904
  22. Otta, S., & Swain, B. (2019). Utility of rapid diagnostic kit tests for diagnosis of suspected dengue fever. International Journal of Research in Medical             Sciences, 7(5), 1670. https://doi.org/10.18203/2320-6012.IJRMS20191656
  23. Riaz, M., Harun, S. N. B., Mallhi, T. H., Khan, Y. H., Butt, M. H., Husain, A., khan, M. M., & Khan, A. H. (2024). Evaluation of clinical and laboratory             characteristics of dengue viral infection and risk factors of dengue             hemorrhagic fever: a multi-center retrospective analysis. BMC Infectious             Diseases, 24. https://doi.org/10.1186/s12879-024-09384-z
  24. Rohini, B. B., Radhika, R., Babu, CH. V. S., & Rakesh, K. (2024). Clinical             manifestations and laboratory profile of dengue fever cases at the time of         presentation in tertiary care hospital. International Journal of Advanced             Research. https://doi.org/10.21474/ijar01/18176
  25. Salvi, D., & Moradia, D. (2020). Assessment of clinical and haematological profile in dengue fever. International Journal of Research in Medical Sciences,             8(12), 4288. https://doi.org/10.18203/2320-6012.IJRMS20204970
  26. Sa-ngamuang C, Haddawy P, Luvira V, Piyaphanee W, Iamsirithaworn S, Lawpoolsri S(2018) Accuracy of dengue clinical diagnosis with and without             NS1 antigen rapid test: Comparison between human and Bayesian network           model decision. PLoS Negl Trop Dis 12(6): e0006573.             https://doi.org/10.1371/journal.pntd.0006573
  27. Sharada T, Raghunath P., Suma N. (2021) Detection of NS1 antigen, IgM and IgG  antibodies  using a commercial Dengue rapid test kit for the diagnosis of             dengue infection in  patients with acute febrile illness. Indian J Microbiol Res 2021;8(3):235-238
  28. Sharma, A., Jain, R., Niranjan, A. K., & Iyengar, S. (2022). Clinicopathological hemetological   and molecular study of dengue suspected pateints -a             prospective study in tertiary care hospital. PARIPEX INDIAN JOURNAL OF       RESEARCH, 5–8.https://doi.org/10.36106/paripex/8702146
  29. Singh S.P, Nayak M, Singh M, Kshitij R, Singh S. (2019) Clinical profile of dengue fever patients in tertiary care hospital of North India. Int J Pediatr             Res.;6(03):129-133.doi:10.17511/ijpr.2019.i03.05
  30. Solanke, S. N., Pohekar, A. S., & Pohekar, J. A. (2019). Clinical and laboratory profile of dengue fever: a retrospective study. International Journal of Advances in Medicine, 6(4), 1254–1258. https://doi.org/10.18203/2349-            3933.IJAM20193280
  31. Talari, S. R., & Belavadi, G. B. (2021). A clinical and biochemical laboratory profile to measure the severity of dengue fever in paediatric population and their             outcome. International Journal of Contemporary Pediatrics, 8(3), 535. https://doi.org/10.18203/2349-3291.IJCP20210659
  32. Villalon, M. R., Ramos, M., & Tiu, J. D. (2021). Clinical and Laboratory Profile of Dengue Fever in Elderly Patients Admitted in a Tertiary Hospital from 2013             to 2018. 7(3). https://doi.org/10.23937/2474-3658/1510200