Eleanor Serrame | Clara Lim-sylianco
Discipline: agriculture food and related studies
When dimethybenzanthracene was used as the initiator and croton oil as the promoter, 67% of the experimental mice developed skin tumors, 50% had liver tumors, and 33% had colon tumors. These were observed after 20 weeks. Complete inhibition of formation of all types of tumors was exhibited by decoction from mango bark and expressed juices from leaves of guava, sulasi, kalatsutsi, yerba buena, pandan, kinchay, sabila, damong Maria, mayana and flowers of santan pula and santan dilaw. Partial inhibition of tumor formation was exhibited by expressed juice from garlic bulbs, leaves of alagaw, flowers from gumamela and decoction from kogon roots and leaves of romero. Expressed juice from onion bulbs inhibited the development of liver tumors but not skin tumors. It is possible that the test medicinal plants contain constituents that can inhibit the promotion stage of carcinogenesis.