Prostaglandin Synthetase from Philippine Gorgonians
Gisela Conception | Lourdes Cruz
Discipline: Biological and Sport Sciences
Abstract:
Optimm extraction and assay conditions for prostaglandin (PG) synthetase from
Echinogorgia sp., a Philippine coelenterate, were studied. The co-oxidation of
L-epinephrine with arachidonic acid to adenochrome (Abs.max480 nm) was used to
assay PG synthetase activity. Optimum assay temperature wa
References:
- Christ, E. J., & Van Dorp, D. A. (1972). Comparative aspects of prostaglandin biosynthesis in animal tissues. Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 270(4), 537–545.
- Ogata, H., Nomura, T., & Hata, M. (1978). Prostaglandin biosynthesis in the tissue homogenates of marine animals. Bulletin of the Japanese Society of Scientific Fisheries, 44(12), 1367–1370.
- Hinman, J. W. (1972). Prostaglandins from Plexaura homomalla: Ecology, utilization, and conservation of a major medical marine source. Quarterly Review of Biology, 47(4), 440–452.
- Brooks, C. D., & White, G. J. (1972). Prostaglandins from Plexaura homomalla: Ecology, utilization, and conservation of a major medical marine source. The Biological Bulletin, 143(2), 440–452.
- Morse, D. E., Duncan, H., Hooker, N., & Morse, A. (1976). Hydrogen peroxide induces spawning in mollusks, with activation of prostaglandin endoperoxide synthetase. Science, 196(4287), 298–300.
- Samuelsson, B., Granström, E., Green, K., Hamberg, M., & Hammarström, S. (1975). Prostaglandins. Annual Review of Biochemistry, 44(1), 669–695.
- Hamberg, M., & Samuelsson, B. (1973). Detection and isolation of an endoperoxide intermediate in prostaglandin biosynthesis. Proceedings of the National Academy of Sciences, 70(3), 899–903.
- Miyamoto, T., Ogino, N., Yamamoto, S., & Hayaishi, O. (1976). Purification and properties of prostaglandin endoperoxide synthetase from a bovine vesicular gland. Journal of Biological Chemistry, 251(9), 2629–2636.
- Ogino, N., Ohki, S., Yamamoto, S., & Hayaishi, O. (1978). Prostaglandin endoperoxide synthetase from bovine vesicular gland: Microsomal purifications and characterization as a hemoprotein. Journal of Biological Chemistry, 253(14), 5061–5068.
- Van der Ouderaa, F. J., Buytenhek, M., Nugteren, D. H., & Van Dorp, D. A. (1977). Purification and characterization of prostaglandin endoperoxide synthetase from sheep vesicular glands. Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 487(2), 315–331.
- Van der Ouderaa, F. J., Buytenhek, M., & Van Dorp, D. A. (1980). Characterization of prostaglandin $H_2$ synthetase. Advances in Prostaglandin and Thromboxane Research, 6, 139–144.
- Morse, D. E., Kayne, M., Tidyman, M., & Anderson, S. (1978). Capacity for biosynthesis of prostaglandin-related compounds: Distribution and properties of the rate-limiting enzyme in hydrocorals, gorgonians, and other coelenterates of the Caribbean and Pacific. The Biological Bulletin, 154(3), 440–452.
- Crook, D., Collins, A. J., Bacon, P. A., & Chan, R. (1976). Prostaglandin synthetase activity from human rheumatoid synovial microsomes. Annals of the Rheumatic Diseases, 35(4), 327–331.
- Appleton, R. A., & Brown, K. (1979). Conformational requirements at the prostaglandin cyclooxygenase reception site. Agents and Actions Supplements, 4, 188–192.
- Roth, G. J., Stanford, N., Jacobs, J. W., & Majerus, P. W. (1977). Acetylation of prostaglandin synthetase by aspirin: Purification and properties of the acetylated protein from sheep vesicular gland. Biochemistry, 16(19), 4244–4248.
- Roth, G. J., & Siok, C. J. (1978). Acetylation of the $NH_2$-terminal serine of prostaglandin synthetase by aspirin. Journal of Biological Chemistry, 253(11), 3782–3784.
- Corey, E. J., Washburn, W. N., & Chen, J. C. (1973). Studies on the prostaglandin $A_2$ synthetase complex of Plexaura homomalla. Journal of the American Chemical Society, 95(6), 2054–2055.
- Lowry, O. H., Rosebrough, N. J., Farr, A. L., & Randall, R. J. (1951). Protein measurement with the Folin phenol reagent. Journal of Biological Chemistry, 193(1), 265–274.
- Bayer, F. M. (1982). Personal communication.
- National Science Development Board. (n.d.). Study support and Marine Science Center procurement recognition documentation.