Mutagenicity Potential of Some Drugs
Clara Lim-sylianco
Discipline: subjects allied to medicine
Abstract:
A number of man-made chemicals in widespread use have been shown to
be mutagenic in subhuman experimental systems. This poses the possibility that
such chemicals may constitute a potential genetic hazard for man both for the
contemporary generation and for the future generation.
References:
- Herbst, A. L., et al. N. England J. of Med. 284: 878 (1971).
- Herbst, A. L. J. Toxicol. and Environ. Health. Suppl. 1: 13, (1976).
- Metzler, M. J. Toxicol. and Environ. Health. Suppl. 1: 21, (1976).
- Rey, V. A. et al. J. Toxicol. and Environ. Health. 1: 21, (1975).
- Hartman, P. E. and Hubert, P. B. J. Toxicol. and Environ. Health. 1: 243 (1975).
- Sieber, S. M. and Adams, R. H. J. Toxicol. and Environ. Health. 1: 309 (1975).
- Klamerth, O. L. Mutation Res. 35: 53 (1976).
- Freese, E., et al. Mutation Res. 5: 343 (1968).
- Rosenkranz, H. L. and Carr, H. S. Lancet. 1: 1354 (1971).
- Rohrborn, G., et al. Mutation Res. 16: 189 (1972).
- Ames, B. N. Chemical Mutagens. 1: 267 (1971).
- Schmid, W. Agents and Actions. 3: 77 (1973).
- Hayatsu, et al. Biochem. Biophys. Acta. 123: 445 (1967).