Inhibitory Effects Of Three Philippine Medicinal Plants On Somatic And Germ Cell Genotoxicity
Gemma P. Geslani | C.y. Lim-sylianco | Angelita Reyes
Abstract:
Three medicinal plants, ampaJaya. kamias and makabuhay possessing fertility regulating
properties were screened for mutagenetic and antimutagenetic activity.
The micronucleus Lesl showed that the plants did not have chromosome-breaking effects on
mammalian somatic cells. Rather, they were anticlascogenic against dimethylnitrosamine (DMN) and
tetracycline HCI. The dominant lethal assay proved that the samples were non-mutagenic to germ
cells. The test plants also exhibited anligenotoxicity against tetracycline HCI.
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