Baldomero M. Olivera | David R. Hillyard | Jean Rivier | Scott R. Woodward | William R. Gray | Gloria Corpuz | Cruz J. Lourdes
Several hundred species of Con.us snails produce a wide array of small (12-30 AA) and mostly tightly disulfide bonded peptide ligands with high affinity for a diverse set of receptor and ion channel types. These include nicotinic acetylcholine receptors, neuronal calcium channels, muscle sodium channels, vasopressin receptors, and N-methyl-D-aspartate (NMDA) receptors. Some general features of the structure, function, and evolution of biologically active peptides isolated from Conus venom are presented. In: Marine Toxins: Origin, Structure, and Molecular Phamacology. S. Hall and G. Strichartz, ACS Symposium Series, American Chemical Sovety, West DC pp 256-278.
ISSN 2719-1990 (Print)
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