Activities of amylase and lipase in the pancreas and duodenal chyme were compared between 36 native and 36 broiler chicks at 1, 7, 14 and 21 days after hatching. The specific activities of amylase and lipase in the pancreas of both native and broiler chicks increased rapidly to its maximum at day 21. In the duodenal chyme of commercial broiler chicks, the specific activity of both amylase and lipase increased up to its maximum at the age of 14 days, which then decreased thereafter. The specific activity of amylase in the duodenal chyme of native chicks was observed to decrease from days 1-14. On the other hand, duodenal lipase in native chicks was observed to increase only at the first week after hatching. Amylase in both pancreas and duodenal chyme of broiler chicks showed higher specific activity than in native chicks. Broiler's pancreatic lipase had higher activity as compared to that of native chick. On the other hand, similar activities of duodenal amylase were observed in both birds on the day after hatching.