Pre-surgical and post-surgical aquapuncture using antibiotics was used to determine whether this can enhance survival rate, wound healing rate and blood cellular responses of goats after rumenotomy. Ten native goats of both sexes were divided randomly into two groups, control and treatment, consisting of five animals each. For the control group, penicillin-streptomycin combination was injected intramuscularly through the gluteal muscle while for the treatment group, the same solution was injected at Acupoints #01 and #34. Administration of the antibiotics for both groups was done one day before surgery and three consecutive days post-operatively. Survival rate, wound healing rate and blood cellular responses were evaluated. All goats remained alive one month after surgery. At the first five days post-surgery, there was a faster wound healing rate in the treatment group compared to the control; at day 15, both groups had 100% healing rate. No significant differences were observed in the blood cellular responses of goats before and after surgery in both control and treatment groups.